MATERNAL MORTALITY DUE TO HELLP SYNDROME: PROFILE INTERFERENCE, CLINICAL AND GYNECOLOGICAL CONDITIONS DURING PREGNANCY

Abstract

Objective: To analyze the correlation between the profile, clinical and gynecological conditions of the pregnant woman and maternal mortality caused by HELLP (Haemolysis, Elevated Liver Enzymes and Low Platelets) syndrome. Material and Method: Correlational, cross-sectional, and retrospective study based on 143 medical records (from 2015 to 2019) of pregnant women, coming from the Alto Sertão Produtivo Baiano region in Northeast Brazil, who were diagnosed with HELLP syndrome. Data collection took place in February and June 2019. Intentional sampling was used, disregarding sample size calculation, as the aim was to include all pregnant women who had developed this syndrome. Two checklists consisting of structured questions referring to the women characterization, their concepts, the gestational process and maternal clinical conditions were used as instruments. The variables were processed using the Statistical Package for the Social Sciences version 22 software. Simple frequency analysis of the variables and correlations with maternal mortality were performed using Pearson’s test. Significance level was considered to be less than or equal to 5% (0.05). Results: The clinical conditions of the current pregnancy that showed significant correlations with maternal mortality resulting from the syndrome were: modes of delivery (p= 0.023), eclampsia (p= 0.000), at least two symptoms of severity and complication (p= 0.005), as well as the time between diagnosis of the syndrome and delivery (p= 0.015). Conclusion: Only four variables on the clinical conditions of the current pregnancy interfered with maternal mortality due to HELLP syndrome, following the correlation with the time between diagnosis and delivery, which has not been recorded in scientific literature.