Efecto regenerador del ácido hialurónico en defectos óseos circunferenciales en ratas albinas Wistar.
DOI:
https://doi.org/10.17126/%25xPalabras clave:
Ácido hialurónico, regeneración ósea, cicatrización de heridas, matriz ósea, ratas wistar, materiales biocompatiblesResumen
Objetivo: Determinar el efecto regenerador del ácido hialurónico en defectos óseos circunferenciales en ratas albinas Wista. Material y Métodos: Se diseñó un estudio de tipo experimental y se trabajó con 15 ratas albinas Wistar (todas macho) de 4 meses de edad y con un peso entre 250 a 350 gr. Se crearon en todas 2 defectos óseos circunferenciales de 3mm de diámetro y 0.8 mm de profundidad en la calota del hueso parietal (a ambos lados de la línea media). Un defecto fue rellenado con una matriz ósea desmineralizada (grupo control); mientras que el otro defecto fue rellenado con la combinación de una matriz ósea desmineralizada más el ácido hialurónico (grupo experimental). Se realizó la eutanasia a 05 ratas de experimentación a los 30, 60 y 90 días postquirúrgicos y se evaluaron histológicamente siguiendo los parámetros propuestos por Heiple. Resultados: El grupo experimental presentó un mejor grado de regeneración ósea en los 30 y 60 días postoperatorios. Conclusiones: El ácido hialurónico es eficaz en la regeneración ósea de defectos óseos circunferenciales.
Descargas
Citas
Lobbezoo F, Ahlberg J, Raphael K.G, Wetselaar P, Glaros A.G, Kato T, Santiago V, Winocur E, De Laat A, De Leeuw R, Koyano K, Lavigne G.J, Svensson P, Mandfredini D. International consensus on the assessment of bruxism: Report of a work in progress. J Oral Rehabil. 2018; 45(11): 837–44.
Raphael KG, Santiago V, Lobbezoo F. Bruxism is a continuously distributed behavior, but disorder decisions are dichotomous. J Oral Rehabil. 2016; 43:802-3.
Cavallo P, Carpinelli L, Savarese G. Perceived stress and bruxism in university students. BMC Res Notes. 2016; 9(1):514.
Jokubauskas L, Baltrušaityt? A, Pilei?ikien? G, Žekonis G. Interrelationships between distinct circadian manifestations of possible bruxism, perceived stress, chronotype and social jetlag in a population of undergraduate students. Chronobiol. Int. 2019;36(11):1558-69.
Serra-Negra JM, Scarpelli AC, Tirsa-Costa, D., Guimarães FH, Pordeus IA, Paiva S M. Sleep Bruxism, Awake Bruxism and Sleep Quality among Brazilian Dental Students: A Cross-Sectional Study. Brazilian Dent J. 2014; 25(3), 241–7.
Tavares L, da Silva Parente Macedo L, Duarte C, de Goffredo Filho G, de Souza Tesch R. Cross-sectional study of anxiety symptoms and self-report of awake and sleep bruxism in female TMD patients. CRANIO. 2016;34(6):378-381.
Phuong NTT, Ngoc VTN, Linh LM, Duc NM, Tra NT, Anh LQ. Bruxism, Related Factors and Oral Health-Related Quality of Life Among Vietnamese Medical Students. Int J Environ Res Public Health. 2020;17(20):7408.
Nogueira Coutinho E, Pereira Rodrigues dos Santos K, Henrique Barros Ferreira E, Grailea Silva Pinto R, de Oliveira Sanchez M. Association between self-reported sleep bruxism and temporomandibular disorder in undergraduate students from Brazil. CRANIO. 2018;38(2):91-98.
Ohlmann B, Bömicke W, Habibi Y, Rammelsberg P, Schmitter M. Are there associations between sleep bruxism, chronic stress, and sleep quality? J Dent. 2018; 74:101-6.
Abekura H, Tsuboi M, Okura T, Kagawa K, Sadamori S, Akagawa Y. Association between sleep bruxism and stress sensitivity in an experimental psychological stress task. Biomed Res J. 2011;32(6):395-9.
Winocur E, Uziel N, Lisha T, Goldsmith C, Eli I. Self-reported bruxism-associations with perceived stress, motivation for control, dental anxiety and gagging. J Oral Rehabil. 2011;38(1):3-11
Gedefaw A, Tilahun T, Asefa A. Predictors of self-reported academic performance among undergraduate medical students of Hawassa University, Ethiopia. Adv Med Educ Pract. 2015;6: 305–15.
Balaji NK, Murthy PS, Kumar DN, Chaudhury S. Perceived stress, anxiety, and coping states in medical and engineering students during examinations. Ind Psychiatry J. 2019; 28 (1): 86-97.
Sohail N. Stress and academic performance among medical students. J Coll Physicians Surg Pak. 2013; 23(1):67-71.
Wijekoon CN, Amaratunge H, de Silva Y, Senanayake S, Jayawardane P, Senarath U. Emotional intelligence and academic performance of medical undergraduates: a cross-sectional study in a selected university in Sri Lanka. BMC Medical Education, 2017;17(1):176.
Masud S, Mufarrih S, Qureshi N, Khan F, Khan S, Khan M. Academic Performance in Adolescent Students: The Role of Parenting Styles and Socio-Demographic Factors – A Cross Sectional Study From Peshawar, Pakistan. Front Psychol. 2019; 10:2497
Ordóñez-Plaza M, Villavicencio-Caparó É, Alvarado-Jiménez O, Vanegas-Avecillas M. Prevalencia de bruxismo de vigilia evaluado por auto-reporte en relación con estrés, ansiedad y depresión. Rev Estomatol Herediana. 2016; 26(3):147-55.
Chatzopoulos G, Wolff L. Symptoms of temporomandibular disorder, self-reported bruxism, and the risk of implant failure: A retrospective analysis. Cranio 2018; 38(1):50-7.
Chain R, Cruz Ramírez N, Martínez Morales M, Jácome N. Examen de selección y probabilidades de éxito escolar en estudios superiores. Estudio en una universidad pública estatal mexicana. Rev Electrónica de Investigación Educativa. 2003; 5(1):1-17.
Ñaupari F. Evaluación del rendimiento académico de estudiantes universitarios en la modalidad presencial y virtual. A Punt. Cienc Soc 2014; 4(1):69-76.
Jun D, Johnston V, Kim J, O’Leary S. Cross-cultural adaptation and validation of the Depression, Anxiety and Stress Scale-21 (DASS-21) in the Korean working population. Work. 2018;59(1):93-102.
Gloster AT, Rhoades HM, Novy D, Klotsche J, Senior A, Kunik M, Wilson N, Stanley MA. Psychometric properties of the Depression Anxiety and Stress Scale-21 in older primary care patients. J Affect Disord. 2008;110(3):248-59.
Román F, Santibáñez P, Vinet E. Uso de las Escalas de Depresión Ansiedad Estrés (DASS-21) como Instrumento de Tamizaje en Jóvenes con Problemas Clínicos. Acta investigación psicol. 2016;6(1):2325-36.
Vera-Romero O, Vera-Romero F. Evaluación del nivel socioeconómico: presentación de una escala adaptada en una población de Lambayeque. Rev Cuerpo Méd. 2013; 6(1):41-4.
Mehrotra D, Kumar K, Kumar S, Tiwari S, Kumar V, Dwivedi R. Reliability and psychometric validity of Hindi version of Depression, Anxiety and Stress Scale-21 (DASS-21) for Hindi speaking Head Neck Cancer and Oral Potentially Malignant Disorders Patients. J Cancer Res Ther. 2019; 15(3):653.
Beaufort I, De Weert-Van Oene G, Buwalda V, De Leeuw J, Goudriaan A. The Depression, Anxiety and Stress Scale (DASS-21) as a Screener for Depression in Substance Use Disorder Inpatients: A Pilot Study. Eur Addict Res. 2017; 23(5):260-8.
Henry J, Crawford J. The short-form version of the Depression Anxiety Stress Scales (DASS-21): Construct validity and normative data in a large non-clinical sample. Br J Clin Psychol. 2005; 44(2):227-39.
Quadri M, Mahnashi A, Al Almutahhir A, Tubayqi H, Hakami A, Arishi M. Alamir A. Association of Awake Bruxism with Khat, Coffee, Tobacco, and Stress among Jazan University Students. Int J Dent.2015; 2015:1-5.
Serra-Negra J, Dias R, Rodrigues M, Aguiar S, Auad S, Pordeus I. Self-reported awake bruxism and chronotype profile: a multicenter study on Brazilian, Portuguese and Italian dental students. CRANIO. 2019; 25:1-6.
Santos Sousa H, Moura de Lima M, Dantas N, Quaresma R, Silva de Moura M, Almeida L. Prevalence and associated factors to sleep bruxism in adolescents from Teresina, Piauí. Rev Bras Epidemiol 2018; 21:1-11.
Blanco Aguilera A, Gonzalez Lopez L, Blanco Aguilera E, De la Hoz Aizpurua J, Rodriguez Torronteras A, Segura Saint-Gerons R. Relationship between self-reported sleep bruxism and pain in patients with temporomandibular disorders. J Oral Rehabil. 2014;41(8):564-72.
Alkhatatbeh MJ, Hmoud ZL, Abdul-Razzak KK, Alem EM. Self-reported sleep bruxism is associated with vitamin D deficiency and low dietary calcium intake: a case-control study. BMC Oral Health. 2021;21(1):21
Marín M, Rodríguez Y, Gamboa E, Ríos J, Rosas J, Mayta-Tovalino F. Level of work stress and factors associated with bruxism in the military crew of the Peruvian Air Force. Med J Armed Forces India. 2019;75(3):297-302.
Seraj B, Shahrabi M, Ghadimi S, et al. The Prevalence of Bruxism and Correlated Factors in Children Referred to Dental Schools of Tehran, Based on Parent's Report. Iran J Pediatr. 2010;20(2):174-180.
Ya?ci ?, Ta?delen Y, Kivrak Y. Childhood Trauma, Quality of Life, Sleep Quality, Anxiety and Depression Levels in People with Bruxism. Noro Psikiyatr Ars. 2020;57(2):131-5.
Garrett AR, Hawley JS. SSRI-associated bruxism: A systematic review of published case reports. Neurol Clin Pract. 2018;8(2):135-41.
Massignan C, de Alencar N A, Soares JP, Santana CM, Serra-Negra J, Bolan M, Cardoso M. Poor sleep quality and prevalence of probable sleep bruxism in primary and mixed dentitions: a cross-sectional study. Sleep and Breathing. 2019;23(3):935-41.
Wetselaar P, Vermaire E, Lobbezoo F, Schuller A. The prevalence of awake bruxism and sleep bruxism in the Dutch adult population. Journal of oral rehabilitation. 2019;46(7):617-623.
Serra-Negra J, Lobbezoo F, Correa-Faria P, Lombardo L, Siciliani G, Stellini E. Relationship of self-reported sleep bruxism and awake bruxism with chronotype profiles in Italian dental students. CRANIO. 2018;37(3):147-52.
Winocur E, Messer T, Eli I, et al. Awake and Sleep Bruxism Among Israeli Adolescents. Front Neurol. 2019;10:443.
Jiménez-Silva A, Peña-Durán C, Tobar-Reyes J, Frugone-Zambra R. Sleep and awake bruxism in adults and its relationship with temporomandibular disorders: A systematic review from 2003 to 2014. Acta Odontol Scand. 2016;75(1):36-58.
Seo D, Ahluwalia A, Potenza MN, Sinha R. Gender differences in neural correlates of stress-induced anxiety. J Neurosci Res. 2017;95(1-2):115-25.
Machado N, Costa Y, Quevedo H, Stuginski-Barbosa J, Valle C, Bonjardim L, Garib DG, Conti P. The association of self-reported awake bruxism with anxiety, depression, pain threshold at pressure, pain vigilance, and quality of life in patients undergoing orthodontic treatment. J Appl Oral Sci. 2020; 28:1-7.
Soto-Goñi XA, Alen F, Buiza-González L, Marcolino-Cruz D, Sánchez-Sánchez T, Ardizone-García I, Aneiros-López F, Jiménez-Ortega L. Adaptive Stress Coping in Awake Bruxism. Front Neurol. 2020;11:564431.
Ono Y, Yamamoto T, Kubo KY, Onozuka M. Occlusion and brain function: mastication as a prevention of cognitive dysfunction. J Oral Rehabil. 2010; 37:624–40.
Ahlberg J, Rantala M, Savolainen A, Suvinen T, Nissinen M, Sarna S. Reported bruxism and stress experience. Community Dent Oral Epidemiol. 2002; 30:405–8.
Fernandez P, Delgado R, Castellanos J. Alteraciones del sueño y bruxismo. Rev ADM. 2018; 75 (4): 187-95
Lavigne G, Khoury S, Abe S, Yamaguchi T, Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil. 2008;35(7):476-94.
Del Toro A, Gorguet Marlen, Pérez Y, Ramos D. Academic stress in first year medicine students with low school performance. Medisan, 2011; 15(1): 17-22.
Wieckiewicz M, Paradowska-Stolarz A, Wieckiewicz W. Psychosocial Aspects of Bruxism: The Most Paramount Factor Influencing Teeth Grinding. Biomed Res Int. 2014; 2014:1-7.
Raphael KG, Santiago V, Lobbezoo F. Is bruxism a disorder or a behaviour? Rethinking the international consensus on defining and grading of bruxism. J Oral Rehabil. 2016; 43(10): 791–8.
Gao Y, Hu D, Peng E, Abbey C, Ma Y, Wu C, Chang C, Hung W, Rozelle S. Int J Environ Res Public Health. 2020; 17(8): 2778.
Alfonso B, Calcines M, Monteagudo R, Nieves Z. Estrés académico. Rev Edumecentro.2015; 7(2): 163-78.
Puddey IB, Mercer A, Carr SE. Relative progress and academic performance of graduate vs undergraduate entrants to an Australian medical school. BMC Med Educ. 2019;19(1):159.
Hayat AA, Shateri K, Amini M, Shokrpour N. Relationships between academic self-efficacy, learning-related emotions, and metacognitive learning strategies with academic performance in medical students: a structural equation model. BMC Med Educ. 2020;20(1):76.
Paesani D, Lobbezoo F, Gelos C, Guarda-Nardini L, Ahlberg J, Manfredini D. Correlation between self-reported and clinically based diagnoses of bruxism in temporomandibular disorders patients. J Oral Rehabil. 2013;40(11):803-9.
Publicado
Cómo citar
Número
Sección
Derechos de autor 2021 Universidad de Concepción
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Este es una Revista de acceso abierto distribuido bajo los términos de Creative Commons Attribution License (CC BY 4.0). Se permite el uso, distribución o reproducción en otros foros, siempre que se acredite al autor o autores originales y a los propietarios de los derechos de autor y se cite la publicación original en esta revista, de acuerdo con la práctica académica aceptada. No se permite ningún uso, distribución o reproducción que no cumpla con estos términos. © 2023.
