Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis

Autores/as

  • Heber Arbildo 1Escuela de Odontología, Universidad Particular de Chiclayo. Chiclayo, Perú
  • Luis Gamarra 4Escuela de Estomatología, Universidad Privada Antonio Guillermo Urrelu. Cajamarca, Perú
  • Sandra Rojas Facultad de Estomatología, Universidad Nacional de Trujillo. Trujillo, Perú
  • Edward Infantes Escuela de Estomatología, Universidad Señor de Sipán. Chiclayo, Perú
  • Cesar Lamas 7Escuela de Odontología, Universidad Católica los Ángeles de Chimbote. Chimbote, Perú
  • Hernán Vásquez 8Facultad de Odontología, Universidad San Martín de Porres. Lima, Perú

DOI:

https://doi.org/10.17126/%25x

Palabras clave:

Platelet rich fibrin, periodontitis, review, meta analysis

Resumen

Background: There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs). One of the current options is the use of platelet-rich fibrin (PRF). Objective: To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis. Materials and Methods: A literature search was conducted up to February 2017 in the following biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials. The selection criteria included: randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession), with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference. Results: The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration.

Descargas

Los datos de descargas todavía no están disponibles.

Publicado

2019-07-03

Cómo citar

Arbildo, H., Gamarra, L., Rojas, S., Infantes, E., Lamas, C., & Vásquez, H. (2019). Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis. Journal of Oral Research, 6(5), 127-135. https://doi.org/10.17126/%x

Número

Sección

Review