Efecto del ibuprofeno y el ultrasonido pulsado de baja intensidad en la reducción del dolor después de la colocación inicial del arco de ortodoncia: un ensayo clínico aleatorizado doble ciego

Autores/as

DOI:

https://doi.org/10.17126/joralres.2022.001

Resumen

Objetivo: Este estudio tuvo como objetivo comparar el efecto del ibuprofeno y el ultrasonido pulsado de baja intensidad (LIPUS) en la reducción del dolor después de la colocación del arco inicial en pacientes de ortodoncia.
Material y Métodos: Este estudio de ensayo clínico doble ciego se llevó a cabo en 60 candidatas a tratamiento de ortodoncia fija referidas al Departamento de Ortodoncia de la Facultad de Odontología de la Universidad de Ciencias Médicas de Mashhad, Mashhad, Irán, durante 2015-2016. Los sujetos se dividieron en cuatro grupos: ibuprofeno, LIPUS, placebo y LIPUS simulado. Se entregó un cuestionario y un bloque de silicona cúbica rectangular y flexible a cada paciente para registrar la intensidad del dolor según la escala analógica visual en puntos de tiempo específicos (es decir, 2 h, 6 h, hora de acostarse, 2do, 3er y 7mo día después de la colocación del arco) al morder el bloque de silicona con los dientes anteriores y posteriores, y sin morder en absoluto. Se utilizó el análisis de varianza de medidas repetidas para comparar la intensidad del dolor en diferentes momentos.
Resultados: La comparación de la intensidad del dolor en varios puntos de tiempo mostró que las puntuaciones medias de dolor más altas y más bajas se informaron a la hora de acostarse y siete días después de la intervención (p<0,001). En cada una de las tres condiciones (es decir, al morder el bloque de silicona con los dientes anteriores y posteriores, y sin morder) en seis momentos (2 h, 6 h, antes de acostarse 2do, 3er y 7mo día después de la colocación del arco), no se observó diferencia significativa en la severidad del dolor (p>0.05).
Conclusión: En conclusión, LIPUS (con una frecuencia de 1 MHz y una intensidad de 100 mW) y el ibuprofeno no tienen efectos significativos en la reducción de la severidad del dolor en diferentes puntos de tiempo y diversas condiciones en pacientes de ortodoncia.

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[1]. Wishney M. Potential risks of orthodontic therapy: a critical review and conceptual framework. Aust Dent J. 2017 Mar;62 Suppl 1:86-96. doi: 10.1111/adj.12486. PMID: 27868202.

[2]. Jain S, Sharma P, Shetty D. Comparison of two different initial archwires for tooth alignment during fixed orthodontic treatment-A randomized clinical trial. J Orthod Sci. 2021 Aug 4;10:13. doi: 10.4103/jos.JOS_17_20. PMID: 34568209; PMCID: PMC8423150.

[3]. Heravi F, Bagheri H, Rangrazi A, Zebarjad SM. An in vitro study on the retentive strength of orthodontic bands cemented with CPP-ACP-containing GIC. Mater Res Express. 2016;3(12):125401. doi:10.1088/2053-1591/3/ 12/125401.

[4]. Lai YC, Yap AU, Türp JC. Prevalence of temporomandibular disorders in patients seeking orthodontic treatment: A systematic review. J Oral Rehabil. 2020 Feb;47(2):270-280. doi: 10.1111/joor.12899. Epub 2019 Nov 7. PMID: 31638281.

[5]. Farzanegan F, Ameri H, Miri Soleiman I, Khodaverdi E, Rangrazi A. An In Vitro Study on the Effect of Amorphous Calcium Phosphate and Fluoride Solutions on Color Improvement of White Spot Lesions. Dent J (Basel). 2018 Jun 22;6(3):24. doi: 10.3390/dj6030024. PMID: 29932119; PMCID: PMC6162429.

[6]. Farzanegan F, Ameri H, Miri Soleiman I, Khodaverdi E, Rangrazi A. An In Vitro Study on the Effect of Amorphous Calcium Phosphate and Fluoride Solutions on Color Improvement of White Spot Lesions. Dent J (Basel). 2018 Jun 22;6(3):24. doi: 10.3390/dj6030024. PMID: 29932119; PMCID: PMC6162429.

[7]. Ahiskalioglu A, ?nce ?, Aksoy M, Yalcin E, Ahiskalioglu EO, Kilinc A. Effects of a Single-Dose of Pre-Emptive Pregabalin on Postoperative Pain and Opioid Consumption After Double-Jaw Surgery: A Randomized Controlled Trial. J Oral Maxillofac Surg. 2016 Jan;74(1):53.e1-7. doi: 10.1016/j.joms.2015.09.008. Epub 2015 Sep 21. PMID: 26433040.

. Long H, Wang Y, Jian F, Liao LN, Yang X, Lai WL. Current advances in orthodontic pain. Int J Oral Sci. 2016 Jun 30;8(2):67-75. doi: 10.1038/ijos.2016.24. PMID: 27341389; PMCID: PMC4932774.

[9]. Krishnan V. Orthodontic pain: from causes to management--a review. Eur J Orthod. 2007 Apr;29(2):170-9. doi: 10.1093/ejo/cjl081. PMID: 17488999.

[10]. Scribante A, Gallo S, Celmare RL, D'Antò V, Grippaudo C, Gandini P, Sfondrini MF. Orthodontic debonding and tooth sensitivity of anterior and posterior teeth. Angle Orthod. 2020 Nov 1;90(6):766-773. doi: 10.2319/022620-134.1. PMID: 33378511; PMCID: PMC8028440.

[11]. Al-Melh MA, Badr H, Andersson L. Comparison between Topical and Injection Anesthetics on Pain Related to Orthodontic Miniscrew Placement: A Split-mouth Study. J Contemp Dent Pract. 2021 Jun 1;22(6):637-643. PMID: 34393120.

[12]. Gargya I, Singh B, Talnia S. NSAIDS (Non-Steroidal Anti-Inflammatory Drugs)-Their Effects and Side Effects in Orthodontic Therapy-A Review. Dental Journal of Advance Studies. 2017;5(01):008-13.

[13]. Matusiak R, Harley KE. Paracetamol overdose in a teenager following placement of a fixed appliance. Dent Update. 2009 Jan-Feb;36(1):33-5. doi: 10.12968/denu.2009.36.1.33. PMID: 19294834.

[14]. Tehranchi A, Badiee M, Younessian F, Badiei M, Haddadpour S. Effect of Low-intensity Pulsed Ultra-sound on Postorthognathic Surgery Healing Process. Ann Maxillofac Surg. 2017 Jan-Jun;7(1):25-29. doi: 10.4103/ams.ams_57_17. PMID: 28713732; PMCID: PMC5502510.

[15]. Hannouche D, Petite H, Sedel L. Current trends in the enhancement of fracture healing. J Bone Joint Surg Br. 2001 Mar;83(2):157-64. doi: 10.1302/0301-620x.83b2.12106. PMID: 11284556.

[16]. Malizos KN, Hantes ME, Protopappas V, Papachristos A. Low-intensity pulsed ultrasound for bone healing: an overview. Injury. 2006 Apr;37 Suppl 1:S56-62. doi: 10.1016/j.injury.2006.02.037. PMID: 16581076.

[17]. Rivera MEG, García GN, Gómez EM, Méndez MCG, Parra TGH, Ancona MB, Baruch NB. Comparation between the analgesic efectiveness of laser ray vs ketorolaco as measure therapeutic effectiveness in to the dental extraction Rev Med UV. 2011;11(2):6-13.

[18]. Heravi F, Moradi A, Ahrari F. The effect of low level laser therapy on the rate of tooth movement and pain perception during canine retraction. Oral Health Dent Manag. 2014 Jun;13(2):183-8. PMID: 24984620.

[19]. Watson T. Electrotherapy E-Book: evidence-based practice: Elsevier Health Sciences; 2008.

. Gasperini G, Rodrigues de Siqueira IC, Rezende Costa L. Does low-level laser therapy decrease swelling and pain resulting from orthognathic surgery? Int J Oral Maxillofac Surg. 2014 Jul;43(7):868-73. doi: 10.1016/j.ijom.2014.02.015. Epub 2014 Mar 25. PMID: 24679851.

[21]. Patel S, McGorray SP, Yezierski R, Fillingim R, Logan H, Wheeler TT. Effects of analgesics on orthodontic pain. Am J Orthod Dentofacial Orthop. 2011 Jan;139(1):e53-8. doi: 10.1016/j.ajodo.2010.07.017. PMID: 21195257.

[22]. Polat O, Karaman AI, Durmus E. Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain. Angle Orthod. 2005 Sep;75(5):791-6. doi: 10.1043/0003-3219(2005)75[791:EOPIAN]2.0.CO;2. Erratum in: Angle Orthod. 2008 Nov;78(6):976. Erratum in: Angle Orthod. 2008.

[23]. Bradley RL, Ellis PE, Thomas P, Bellis H, Ireland AJ, Sandy JR. A randomized clinical trial comparing the efficacy of ibuprofen and paracetamol in the control of orthodontic pain. Am J Orthod Dentofacial Orthop. 2007 Oct;132(4):511-7. doi: 10.1016/j.ajodo.2006.12.009. PMID: 17920505.

[24]. Shetty S, Shenoy N, Shenoy KA, Unnikrishnan B, Mogra S. Comparison of effects of preoperative piroxicam and ibuprofen on pain after separator placement: a randomized controlled trial. J Orthodontic Res. 2013;1(2):57.

[25]. Walker JB, Buring SM. NSAID impairment of orthodontic tooth movement. Ann Pharmacother. 2001 Jan;35(1):113-5. doi: 10.1345/aph.10185. PMID: 11197570.

. Kehoe MJ, Cohen SM, Zarrinnia K, Cowan A. The effect of acetaminophen, ibuprofen, and misoprostol on prostaglandin E2 synthesis and the degree and rate of orthodontic tooth move-ment. Angle Orthod. 1996;66(5):339-49. doi: 10.1043/0003-3219(1996)066<0339:TEOAIA>2.3.CO;2. PMID: 8893104.

[27]. Steen Law SL, Southard KA, Law AS, Logan HL, Jakobsen JR. An evaluation of preoperative ibuprofen for treatment of pain associated with orthodontic separator placement. Am J Orthod Dentofacial Orthop. 2000 Dec;118(6):629-35. doi: 10.1067/mod.2000.110638. PMID: 11113797.

[28]. Salmassian R, Oesterle LJ, Shellhart WC, Newman SM. Comparison of the efficacy of ibuprofen and acetaminophen in controlling pain after orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 2009 Apr;135(4):516-21. doi: 10.1016/j.ajodo.2007.05.020. PMID: 19361739.

[29]. Kawamoto SA. Acetaminophen versus Ibuprofen for the control of immediate and delayed pain following orthodontic separator placement: University of Missouri--Kansas City; 2010.

[30]. Kohli SS, Kohli VS. Effectiveness of piroxicam and ibuprofen premedication on orthodontic patients' pain experiences. Angle Orthod. 2011 Nov;81(6):1097-102. doi: 10.2319/022411-134.1. Epub 2011 Jun 6. PMID: 21644837; PMCID: PMC8903866.

[31]. Ireland AJ, Ellis P, Jordan A, Bradley R, Ewings P, Atack NE, Griffiths H, House K, Moore MB, Deacon S, Wenger N, Worth V, Scaysbrook E, Williams JC, Sandy JR. Chewing gum vs. ibuprofen in the management of orthodontic pain, a multi-centre randomised controlled trial - the effect of anxiety. J Orthod. 2017 Mar;44(1):3-7. doi: 10.1080/14653125.2016.1277317. PMID: 28248619.

[32]. Murdock S, Phillips C, Khondker Z, Hershey HG. Treatment of pain after initial archwire placement: a noninferiority randomized clinical trial comparing over-the-counter analgesics and bite-wafer use. Am J Orthod Dentofacial Orthop. 2010 Mar;137(3):316-23. doi: 10.1016/j.ajodo.2008.12.021. PMID: 20197167.

[33]. Tanaka E, Kuroda S, Horiuchi S, Tabata A, El-Bialy T. Low-intensity pulsed ultrasound in dentofacial tissue engineering. Ann Biomed Eng. 2015 Apr;43(4):871-86. doi: 10.1007/s10439-015-1274-y. Epub 2015 Feb 12. PMID: 25672801.

[34]. Toy E, Oztürk F, Altindi? S, Kozacio?lu S, Toy H. Effects of low-intensity pulsed ultrasound on bone formation after the expansion of the inter-premaxillary suture in rats: a histologic and immunohistochemical study. Aust Orthod J. 2014 Nov;30(2):176-83. PMID: 25549520.

[35]. Butera A, Gallo S, Maiorani C, Molino D, Chiesa A, Preda C, Esposito F, Scribante A. Probiotic Alternative to Chlorhexidine in Periodontal Therapy: Evaluation of Clinical and Microbiological Parameters. Microorganisms. 2020 Dec 29;9(1):69. doi: 10.3390/microorganisms9010069. PMID: 33383903; PMCID: PMC7824624.

[36]. Costa-Pinto AR, Lemos AL, Tavaria FK, Pintado M. Chitosan and Hydroxyapatite Based Biomaterials to Circumvent Periprosthetic Joint Infections. Materials (Basel). 2021 Feb 8;14(4):804. doi: 10.3390/ma14040804. PMID: 33567675; PMCID: PMC7914941.

[37]. Domínguez A, Gómez C, Palma JC. Effects of low-level laser therapy on orthodontics: rate of tooth movement, pain, and release of RANKL and OPG in GCF. Lasers Med Sci. 2015 Feb;30(2):915-23. doi: 10.1007/s10103-013-1508-x. PMID: 24346335.

[38]. Alan H, Yolcu Ü, Koparal M, Özgür C, Öztürk SA, Malkoç S. Evaluation of the effects of the low-level laser therapy on swelling, pain, and trismus after removal of impacted lower third molar. Head Face Med. 2016 Jul 26;12(1):25. doi: 10.1186/s13005-016-0121-1. PMID: 27457369; PMCID: PMC4960798.

[39]. Sousa MV, Pinzan A, Consolaro A, Henriques JF, de Freitas MR. Systematic literature review: influence of low-level laser on orthodontic movement and pain control in humans. Photomed Laser Surg. 2014 Nov;32(11):592-9. doi: 10.1089/pho.2014.3789. Epub 2014 Oct 21. PMID: 25335088.

[40]. Colagiuri B, Schenk LA, Kessler MD, Dorsey SG, Colloca L. The placebo effect: From concepts to genes. Neuroscience. 2015 Oct 29;307:171-90. doi: 10.1016/j.neuroscience. 2015.08.017. Epub 2015 Aug 10. PMID: 26272535; PMCID: PMC5367890.

[41]. Benedetti F, Mayberg HS, Wager TD, Stohler CS, Zubieta JK. Neurobiological mechanisms of the placebo effect. J Neurosci. 2005 Nov 9;25(45):10390-402. doi: 10.1523/JNEUROSCI.3458-05.2005. PMID: 16280578; PMCID: PMC6725834.

[42]. Sobouti F, Chiniforush N, Saravani HJ, Noroozian M, Cronshaw M, Navaei RA, Rakhshan V, Dadgar S. Efficacy of compound topical anesthesia combined with photobiomodulation therapy in pain control for placement of orthodontic miniscrew: a double-blind, randomized clinical trial. Lasers Med Sci. 2022 Feb;37(1):589-594. doi: 10.1007/s10103-021-03307-z. PMID: 33796965.

[43]. Al Shayea EI. Comparative Assessment between Ibuprofen, Chewing Gum, and Bite Wafers in Pain Control Following First Archwire Placement in Orthodontic Patients. J Contemp Dent Pract. 2020 Apr 1;21(4):416-420. PMID: 32584279.

[44]. Celebi F, Bicakci AA, Kelesoglu U. Effectiveness of low-level laser therapy and chewing gum in reducing orthodontic pain: A randomized controlled trial. Korean J Orthod. 2021 Sep 25;51(5):313-320. doi: 10.4041/kjod.2021.51.5.313. PMID: 34556585; PMCID: PMC8461383.

[45]. Roth PM, Thrash WJ. Effect of transcutaneous electrical nerve stimulation for controlling pain associated with orthodontic tooth movement. Am J Orthod Dentofacial Orthop. 1986 Aug;90(2):132-8. doi: 10.1016/0889-5406(86)90045-4. PMID: 3488674.

Publicado

2022-02-28

Cómo citar

1.
Farzanegan F, Bamrood ZA, Rangrazi A, Shafaee H. Efecto del ibuprofeno y el ultrasonido pulsado de baja intensidad en la reducción del dolor después de la colocación inicial del arco de ortodoncia: un ensayo clínico aleatorizado doble ciego. J Oral Res [Internet]. 28 de febrero de 2022 [citado 29 de marzo de 2024];11(1):1-12. Disponible en: https://revistas.udec.cl/index.php/journal_of_oral_research/article/view/7552

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